AOD-9604

About AOD-9604

AOD-9604 is a modified fragment of human growth hormone (HGH) used in research studying metabolic processes and fat metabolism.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: AOD-9604 is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

AOD-9604 is a synthetic peptide fragment derived from the C-terminus of human growth hormone, studied extensively in lipid metabolism and obesity research. As a research compound, AOD-9604 is investigated for its lipolytic properties without the growth-promoting effects of intact growth hormone.

Key Research Applications

Lipolysis Research: AOD-9604 is utilized in studies examining fat mobilization mechanisms, adipocyte lipolytic pathway activation, and triglyceride breakdown in isolated adipose tissue models.

Metabolic Studies: Research applications include investigation of energy expenditure mechanisms, fatty acid oxidation pathways, and metabolic rate modulation independent of growth hormone receptor activation.

Obesity Research: AOD-9604 is employed in studies exploring therapeutic interventions for excessive adiposity, examining regional fat reduction mechanisms and metabolic improvements in obesity models.

Growth Hormone Fragment Studies: Research utilizes AOD-9604 to investigate separation of GH's lipolytic effects from its growth-promoting, diabetogenic, and IGF-1 elevating activities.

Mechanism of Action

AOD-9604 corresponds to amino acids 176-191 of the C-terminal region of human growth hormone, a region implicated in the lipolytic activity of GH. The peptide is modified with a tyrosine residue at the N-terminus to enhance stability. Research demonstrates that AOD-9604 stimulates lipolysis through mechanisms that do not involve growth hormone receptors, potentially through direct effects on beta-3 adrenergic receptors or via alternative signaling pathways distinct from intact GH, thereby avoiding growth-promoting and glucose metabolism effects.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.