CJC-1295

About CJC-1295

CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH) used in research applications studying growth hormone release mechanisms.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: CJC-1295 is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

CJC-1295 is a synthetic growth hormone-releasing hormone (GHRH) analog peptide utilized in neuroendocrine research laboratories. As a research compound, CJC-1295 is studied for its interactions with growth hormone secretagogue receptor pathways, pituitary gland function, and somatotropic axis regulation.

Key Research Applications

Growth Hormone Research: CJC-1295 is utilized in studies investigating pulsatile GH secretion patterns, somatotroph cell function, and hypothalamic-pituitary axis dynamics in experimental models.

IGF-1 Pathway Studies: Research applications include examination of insulin-like growth factor-1 (IGF-1) production pathways, hepatic IGF-1 synthesis mechanisms, and systemic IGF-1 distribution dynamics.

Metabolic Research: CJC-1295 is employed in studies exploring protein synthesis pathways, lipolytic mechanisms, and glucose metabolism regulation in laboratory settings.

Receptor Binding Studies: Research utilizes CJC-1295 to investigate GHRH receptor affinity, receptor internalization mechanisms, and downstream signaling cascade activation patterns.

Mechanism of Action

CJC-1295 functions through selective binding to growth hormone-releasing hormone receptors (GHRH-R) on pituitary somatotroph cells. The Drug Affinity Complex (DAC) modification extends the peptide's half-life by forming covalent bonds with serum albumin, protecting against enzymatic degradation. Research demonstrates that CJC-1295 activates adenylyl cyclase pathways, increasing intracellular cAMP levels and triggering calcium mobilization, which culminates in growth hormone secretion through exocytosis of secretory granules.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.