Dihexa

About Dihexa

Dihexa is a small peptide used in research studying cognitive enhancement, neurogenesis, and synaptic formation mechanisms.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: Dihexa is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

Dihexa is a synthetic peptide-derived compound studied extensively in neuroscience research for its potent neurotrophic properties. As a research compound, Dihexa is investigated for its effects on synaptogenesis, cognitive enhancement, and potential applications in neurodegenerative disease models.

Key Research Applications

Synaptogenesis Research: Dihexa is utilized in studies examining synaptic formation mechanisms, investigating neuronal connectivity enhancement and synaptic density increases in laboratory models.

Cognitive Research: Research applications include investigation of memory formation mechanisms, examining spatial learning, working memory, and cognitive flexibility in behavioral testing paradigms.

Neurodegenerative Research: Dihexa is employed in studies exploring therapeutic interventions for neurodegenerative conditions, examining protective effects in models of cognitive decline and neuronal loss.

HGF/c-Met Pathway Studies: Research utilizes Dihexa to investigate hepatocyte growth factor (HGF) receptor activation, examining c-Met signaling cascades and downstream neurotrophic effects.

Mechanism of Action

Dihexa functions as a potent activator of hepatocyte growth factor (HGF) receptor c-Met, which is expressed in the central nervous system and plays critical roles in neuronal survival, growth, and synaptic plasticity. Research demonstrates that Dihexa binding to c-Met triggers downstream signaling including PI3K/Akt and MAPK/ERK pathways, promoting dendritic spine formation, synaptic protein expression, and enhancement of long-term potentiation (LTP). The compound shows remarkable potency, with effects observed at sub-nanomolar concentrations in neuronal culture systems.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.