GHRP-2

About GHRP-2

GHRP-2 is a synthetic hexapeptide growth hormone secretagogue used in research applications studying growth hormone pathways.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: GHRP-2 is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

GHRP-2 (Growth Hormone Releasing Peptide-2) is a synthetic hexapeptide growth hormone secretagogue extensively studied in neuroendocrine research. As a research compound, GHRP-2 is investigated for its potent GH-releasing properties, minimal appetite effects, and pituitary gland stimulation mechanisms.

Key Research Applications

Pituitary Function Research: GHRP-2 is utilized in studies examining somatotroph cell activation, growth hormone pulse amplitude modulation, and pituitary responsiveness to secretagogue stimulation.

Synergistic GH Release Studies: Research applications include investigation of GHRP-2 and GHRH analog combinations, examining additive and synergistic effects on growth hormone secretion patterns.

Receptor Pharmacology: GHRP-2 is employed in studies mapping growth hormone secretagogue receptor subtypes, examining receptor-ligand binding kinetics, and signal transduction pathway characterization.

Age-Related GH Research: Studies utilize GHRP-2 to investigate somatopause mechanisms, age-related decline in GH secretory capacity, and pituitary gland senescence in laboratory models.

Mechanism of Action

GHRP-2 functions through high-affinity binding to the GHS-R1a receptor subtype, triggering robust growth hormone release with minimal ghrelin-like appetite stimulation. The peptide activates phospholipase C and protein kinase C pathways, mobilizing intracellular calcium stores and depolarizing somatotroph cell membranes. Research demonstrates that GHRP-2 exhibits approximately 50% greater potency than GHRP-6 in stimulating GH release while producing significantly less appetite stimulation, making it particularly valuable for GH-focused research applications.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.