Hexarelin

About Hexarelin

Hexarelin is a synthetic hexapeptide with strong growth hormone-releasing properties, used in research studying GH receptor interactions.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: Hexarelin is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

Hexarelin is a synthetic hexapeptide growth hormone secretagogue with cardioprotective properties studied extensively in neuroendocrine and cardiovascular research. As a research compound, Hexarelin is investigated for its dual actions on growth hormone release and cardiac tissue protection mechanisms.

Key Research Applications

Cardiovascular Research: Hexarelin is utilized in studies examining cardiac myocyte protection mechanisms, ischemia-reperfusion injury models, and cardioprotective signaling pathways independent of GH release.

GH Secretagogue Studies: Research applications include investigation of potent growth hormone release mechanisms, dose-response relationships, and comparison with other GHRP analogs.

CD36 Receptor Research: Hexarelin is employed in studies exploring scavenger receptor CD36 interactions, which mediate cardiovascular protective effects distinct from GHS-R activation.

Metabolic Cardiology: Studies utilize Hexarelin to investigate metabolic adaptations in cardiac tissue, mitochondrial function regulation, and energy substrate utilization in heart muscle cells.

Mechanism of Action

Hexarelin functions through dual receptor activation mechanisms. It binds to GHS-R1a receptors to stimulate growth hormone release via standard secretagogue pathways. Additionally, Hexarelin demonstrates unique affinity for CD36 scavenger receptors expressed on cardiac myocytes and endothelial cells. Research demonstrates that this CD36 binding activates protective signaling cascades including PI3K/Akt pathways, reduces oxidative stress, and modulates apoptotic mechanisms in cardiac tissue, independent of growth hormone effects.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.