MOTS-c

About MOTS-c

MOTS-c is a mitochondrial-derived peptide used in research studying cellular metabolism, energy production, and metabolic regulation.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: MOTS-c is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a mitochondrial-derived peptide studied in metabolic research and aging biology. As a research compound, MOTS-c is investigated for its regulatory effects on metabolism, mitochondrial function, and cellular energy homeostasis.

Key Research Applications

Metabolic Regulation Research: MOTS-c is utilized in studies examining insulin sensitivity mechanisms, glucose metabolism regulation, and metabolic adaptation to nutrient availability in laboratory models.

Mitochondrial Function Studies: Research applications include investigation of mitochondrial-nuclear communication, mitochondrial biogenesis pathways, and cellular energy production optimization.

Exercise Physiology Research: MOTS-c is employed in studies exploring exercise-induced metabolic adaptations, skeletal muscle metabolic responses, and physical performance enhancement mechanisms.

Aging and Longevity Studies: Research utilizes MOTS-c to investigate age-related metabolic decline, interventions targeting metabolic aging, and mechanisms underlying healthy aging processes.

Mechanism of Action

MOTS-c functions as a signaling peptide encoded within the mitochondrial genome that regulates nuclear gene expression. Research demonstrates that MOTS-c activates AMPK (AMP-activated protein kinase) pathways in skeletal muscle, promoting glucose uptake and utilization. The peptide translocates to the cell nucleus under metabolic stress conditions, where it interacts with transcription factors to regulate gene expression related to antioxidant responses, insulin sensitivity, and metabolic adaptation.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.