Thymosin Alpha-1

About Thymosin Alpha-1

Thymosin Alpha-1 is a peptide used in research studying immune function, T-cell maturation, and immunomodulation.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: Thymosin Alpha-1 is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

Thymosin Alpha-1 is a synthetic peptide corresponding to a biologically active segment of thymopoietin, extensively studied in immunology and host defense research. As a research compound, Thymosin Alpha-1 is investigated for its immunomodulatory properties, T-cell maturation effects, and innate immune system enhancement.

Key Research Applications

T-Cell Research: Thymosin Alpha-1 is utilized in studies examining T-lymphocyte differentiation, thymocyte maturation processes, and T-cell receptor expression in laboratory immunology models.

Innate Immunity Studies: Research applications include investigation of dendritic cell maturation, natural killer cell activation, and macrophage functional enhancement in immune system research.

Cytokine Regulation Research: Thymosin Alpha-1 is employed in studies exploring interferon production, interleukin signaling modulation, and cytokine network regulation in immune responses.

Immunosenescence Research: Studies utilize Thymosin Alpha-1 to investigate age-related immune system decline, thymic involution mechanisms, and interventions targeting immune aging.

Mechanism of Action

Thymosin Alpha-1 functions through multiple immunomodulatory pathways including enhancement of T-cell maturation via actions on thymic epithelial cells, augmentation of MHC class I and II expression on antigen-presenting cells, and modulation of Toll-like receptor (TLR) signaling. Research demonstrates that Thymosin Alpha-1 increases production of IL-2, IL-3, and interferon-gamma while enhancing the cytotoxic activity of natural killer cells and promoting the differentiation of precursor cells into immunocompetent T-lymphocytes.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.