Tirzepatide
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About Tirzepatide
Tirzepatide is a novel synthetic peptide that functions as a dual GIP/GLP-1 receptor agonist, representing a unique class of incretin mimetics in metabolic research. This dual-agonist approach is extensively studied in laboratories investigating synergistic effects of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) pathway activation.
Key Research Applications
Dual Incretin Pathway Research: Tirzepatide is utilized to study the combined effects of GIP and GLP-1 receptor activation on insulin secretion, glucagon regulation, and glucose homeostasis in cellular and tissue models.
Metabolic Syndrome Studies: Research laboratories employ Tirzepatide to investigate mechanisms of body weight regulation, energy expenditure, lipid metabolism, and insulin sensitivity in metabolic research protocols.
Beta Cell Preservation: The peptide is used in pancreatic research to study protective effects on beta cell mass, insulin biosynthesis capacity, and glucose-stimulated insulin secretion mechanisms.
Hepatic Metabolism: Tirzepatide research includes investigating effects on hepatic glucose production, glycogen synthesis, lipogenesis pathways, and NAFLD-related mechanisms in laboratory settings.
Mechanism of Action (Research Context)
In research models, Tirzepatide demonstrates high affinity for both GIP and GLP-1 receptors with modifications that provide extended half-life characteristics. The dual agonism activates both incretin pathways simultaneously, potentially offering synergistic benefits in glucose regulation and metabolic pathway modulation studied in laboratory research.
Product Specifications
Form: Lyophilized sterile powder requiring reconstitution with bacteriostatic water for research use.
Purity: Supplied at ≥98% purity (HPLC verified) for laboratory research applications.
Storage: Store lyophilized powder at -20°C protected from light. After reconstitution, store at 2-8°C and use within manufacturer-specified timeframe.
Important: Tirzepatide is strictly for in-vitro laboratory research only. NOT for human consumption, clinical use, or in-vivo application outside approved research protocols.
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