Melanotan 2

About Melanotan 2

Melanotan 2 is a synthetic analogue of alpha-melanocyte-stimulating hormone used in research studying melanogenesis and melanocortin receptor pathways.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: Melanotan 2 is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

Melanotan-2 is a synthetic analog of alpha-melanocyte stimulating hormone studied in melanocortin receptor research and neuroendocrine biology. As a research compound, Melanotan-2 is investigated for its effects on multiple melanocortin receptor subtypes, melanogenesis, and central nervous system signaling.

Key Research Applications

Melanocortin Receptor Research: Melanotan-2 is utilized in studies examining non-selective melanocortin receptor activation, investigating MC1R, MC3R, MC4R, and MC5R signaling in various tissue and cell models.

Appetite Regulation Studies: Research applications include investigation of MC4R-mediated appetite suppression, examining hypothalamic melanocortin pathways and energy homeostasis regulation in laboratory models.

Sexual Behavior Research: Melanotan-2 is employed in studies exploring central melanocortin effects on sexual motivation and function, examining neural pathways involved in reproductive behaviors.

Pigmentation Research: Studies utilize Melanotan-2 to investigate melanogenesis mechanisms, comparing potency and receptor selectivity with other melanocortin agonists in dermatological research.

Mechanism of Action

Melanotan-2 functions as a non-selective melanocortin receptor agonist with affinity for MC1R, MC3R, MC4R, and MC5R subtypes. The cyclic peptide structure provides enhanced stability and receptor binding compared to linear alpha-MSH. Research demonstrates that Melanotan-2 activates adenylyl cyclase through G-protein coupled receptor mechanisms, increasing cAMP production and triggering diverse downstream effects including melanogenesis via MC1R, appetite suppression and energy expenditure via MC4R, and various neuroendocrine effects through MC3R and MC4R in the central nervous system.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.