Thymosin Beta-4

About Thymosin Beta-4

Thymosin Beta-4 is a naturally occurring peptide used in research studying tissue repair, wound healing, and cellular regeneration.

This research peptide is supplied as a lyophilized powder that requires reconstitution before use in laboratory applications. It is provided at research-grade purity for in-vitro studies only.

Research Applications: Thymosin Beta-4 is used exclusively for laboratory research purposes. It is not intended for human consumption, medical treatment, or any form of in-vivo application.

Storage: Store lyophilized powder at -20°C. After reconstitution, store at 2-8°C and use within the timeframe specified by the manufacturer.

Detailed Research Information

Thymosin Beta-4 is a naturally occurring peptide extensively studied in cellular migration, wound healing, and tissue regeneration research. As a research compound, Thymosin Beta-4 is investigated for its actin-sequestering properties, angiogenic effects, and anti-inflammatory mechanisms.

Key Research Applications

Wound Healing Research: Thymosin Beta-4 is utilized in studies examining cellular migration mechanisms, re-epithelialization processes, and wound closure dynamics in various tissue injury models.

Angiogenesis Studies: Research applications include investigation of endothelial cell migration, capillary tube formation, and vascular network development in tissue regeneration contexts.

Actin Dynamics Research: Thymosin Beta-4 is employed in studies exploring G-actin sequestration, cytoskeletal reorganization, and cell motility mechanisms in laboratory cell culture systems.

Anti-inflammatory Studies: Research utilizes Thymosin Beta-4 to investigate inflammatory response modulation, examining effects on cytokine production, leukocyte infiltration, and tissue inflammation resolution.

Mechanism of Action

Thymosin Beta-4 functions primarily through sequestration of G-actin monomers, regulating actin polymerization dynamics that are essential for cell migration, morphology, and division. Beyond actin binding, research demonstrates that Thymosin Beta-4 promotes angiogenesis through upregulation of vascular endothelial growth factor (VEGF), enhances cellular migration via activation of integrin-linked kinase (ILK) and focal adhesion kinase (FAK), and reduces inflammation by downregulating pro-inflammatory cytokines including TNF-alpha and IL-1beta.

Product Specifications

All listed research peptides are supplied in lyophilized (freeze-dried) powder form and require reconstitution with bacteriostatic water or sterile water before use in laboratory applications. Products are intended exclusively for in vitro research and are not for human consumption.